Single cell magnetic imaging
The in situ measurement of biomolecules inside a single cell is an important goal in life science. Among various imaging techniques, the magnetic resonance imaging (MRI) technique can quickly and non-destructively acquire spin distribution images in vivo. As MRI has almost no damage to organisms, it plays an important role in pathological research, diagnosis, and treatment of diseases. However, the spatial resolution limit of traditional MRI is above micrometers, thus it is impossible to perform molecular-scale MRI in a cell. The researchers break the limit with QDAFM, which enables a 10 nm spatial resolution magnetic imaging of ferritins in a single cell.
Wang, P. et al. Nanoscale magnetic imaging of ferritins in a single cell. Science advances 5, 8038 (2019).
Nano magnetic imaging of ferritin in situ
Schematic diagram of nano magnetic imaging experiment
Topological magnetic structure characterization
Magnetic skyrmions are small swirling topological defects in the magnetization texture. It exhibits rich novel physical properties and provides a new platform for studying topological spintronics. The potential applications include high-density, low-power cost and nonvolatile storage devices. However, the detection of a single skyrmion at room temperature is still challenging. Owing to the high sensitivity and high spatial resolution features, QDAFM demonstrated its ability to solve this long-standing problem by reconstructing the full set of spin textures from a measured stray field.
Dovzhenko, Y. et al. Magnetostatic twists in room-temperature skyrmions explored by nitrogen-vacancy center spin texture reconstruction. Nature Communications 9, 2712 (2018).